3D Model of Lamprey Estrogen Receptor with Estradiol and 15α-Hydroxy-Estradiol
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چکیده
منابع مشابه
3D Model of Lamprey Estrogen Receptor with Estradiol and 15α-Hydroxy-Estradiol
BACKGROUND Lamprey, basal vertebrate, is an important model system for understanding early events in vertebrate evolution. Lamprey contains orthologs of the estrogen receptor [ER], progesterone receptor and corticoid receptor. A perplexing property of lamprey is that 15alpha-hydroxy-steroids are active steroids. For example, 15alpha-hydroxy-estradiol [15alpha-OH-E2] is the estrogen, instead of ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0006038